Our Scientific Evidence – Simplified

We are often asked about the independent Irish research behind our products – what exactly was researched and what did the results show?

So in this blog, we wanted to share a bit more detail on the most important studies carried out on Irish patients at Waterford Institute of Technology over the last 20 years.

Read on to find out what question each research study was designed to test and click the Show Answer button to see what was discovered about MacuPrime.

Q

If a person has very little protective macular pigment, can we rebuild it using MacuPrime supplements?

Some people cannot convert retinal Lutein into Meso-Zeaxanthin meaning they have little or no macular pigment, which causes a dip at the centre of the macula. These people are at higher risk of developing Age-related Macular Degeneration (AMD). In the Central Dip Study, some patients were given MacuPrime (10mg Lutein, 10mg Meso-Zeaxanthin and 2mg Zeaxanthin) and others were given a carotenoid supplement that did not contain Meso-Zeaxanthin.

Central Dip Study – “Macular carotenoid supplementation in subjects with atypical spatial profiles of macular pigment” Nolan, et al Experimental Eye Research, 2012

Q

Do individual carotenoids (e.g. Lutein) have the same antioxidant effect as Lutein, Zeaxanthin and Meso-Zeaxanthin combined?

Some supplements on the market have just one or two carotenoids rather than all three. This study tested the antioxidant effects of individual carotenoids compared to the antioxidant effect of having all three carotenoids together, as are present in MacuPrime.

“Studies on the singlet oxygen scavenging mechanism of human macular pigment” Li, et al Archives of Biochemistry & Biophysics, 2010

Q

Should we treat early signs of Age-related Macular Degeneration (AMD) with carotenoid supplements instead of waiting until the disease is established?

When diagnosed with early AMD, a person’s biggest fear is losing their vision. MOST study scientists at WIT tested and compared the impact of different macular carotenoid formulations on macular pigment and visual function (contrast sensitivity) in patients showing early signs of AMD.

MOST Study – “Sustained supplementation and monitored response with differing carotenoid formulations in early age-related macular degeneration” Akuffo, et al, Eye, 2015

Q

Can a person with healthy eyes, free of disease benefit from taking a MacuPrime carotenoid supplement?

Research normally focusses on disease prevention or cure – this CREST Normal study was unique in that it studied healthy eyes.  Many people with healthy eyes and 20/20 visual acuity still complain about lack of sharpness in their vision or difficulty driving at night and glare sensitivity. Research has shown that these complaints can be linked to having a low macular pigment & poor contrast sensitivity.

CREST Normal – “Enrichment of Macular Pigment Enhances Contrast Sensitivity in Subjects Free of Retina Disease: Central Retinal Enrichment Supplementation Trials – Report 1” Nolan, et al, IOVS, 2016

Q

Can carotenoid supplementation help people with Age-related Macular Degeneration (AMD)?

50% of people diagnosed with early AMD usually go on to develop advanced AMD and lose their vision. This 3 year research study investigated the impact of MacuPrime PLUS supplementation on a patients visual function.

CREST AMD – “The Impact of Supplemental Antioxidants on Visual Function in Nonadvanced Age-Related Macular Degeneration : A Head-to-Head Randomized Clinical Trial” Akuffo, et al, IOVS, 2017

MacuPrime Products

MacuPrime®

Proven in Irish clinical studies to help rebuild macular pigment, which is important in protecting central vision and may help to combat Age-Related Macular Degeneration
Clear
Product/Amount
Normal RRP
15% Off Price
1 Month Supply
€18.95
€16.11
3 Months Supply
€43.95
€37.36
6 Months Supply
€79.11
€67.24
1 Year Supply
€150.64
€128.04

MacuPrime PLUS®

Delivers the same triple carotenoid formula as MacuPrime® but with added Zinc which helps maintain normal vision and Vitamin C, Vitamin E and Copper, which protect cells from oxidative stress.
Clear
Product/Amount
Normal RRP
15% Off Price
1 Month Supply
€24.95
€21.21
3 Months Supply
€67.35
€57.25
6 Months Supply
€134.76
€114.55

2 Responses

    1. Hi Nicky, thanks for your query. Our products do not contain any fish related ingredients. However, they do contain a small amount of bovine gelatine so are not vegetarian/vegan friendly. Please let me know if you’ve any other queries, best regards Karen

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2 Responses

    1. Hi Nicky, thanks for your query. Our products do not contain any fish related ingredients. However, they do contain a small amount of bovine gelatine so are not vegetarian/vegan friendly. Please let me know if you’ve any other queries, best regards Karen

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Your email address will not be published. Required fields are marked *